Postoperative pain control. Postoperative acute pain control
Conditions
Interventions
Intervention 1: In the study group, 300 milligrams pregabalin, one hour before surgery. Intervention 2: In the control group, 300 milligrams placebo, one hour before surgery.
Treatment - Drugs
Placebo
In the study group, 300 milligrams pregabalin, one hour before surgery
In the control group, 300 milligrams placebo, one hour before surgery
Sponsors
Vice chancellor for research, Tehran University of Medical Sciences and Health Services
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 18-50 yr; ASA Class I- II Exclusion criteria: Systolic Blood pressure less than 90 mmHg; Substance abuse; Pregnancy and breast feeding; Nonsteroidal anti-inflammatory drugs sensitivity; Asthma and Allergic rhinitis, Peptic ulcer disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: At recovery, 30 minutes, 2,4,12 and 24 hours after surgery. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid consumption. Timepoint: 24 hours after surgery. Method of measurement: By PCA.;Nausea & vomiting. Timepoint: 24 hours after surgery. Method of measurement: By asking the patient the question. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahzad Alimian
Rasul Hospital
Outcome results
None listed