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The L-carnitine effect in non alcoholic fatty liver

The L-carnitine effect in the treatment of non alcoholic fatty liver disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201102235893N1
Enrollment
80
Registered
2011-07-30
Start date
2010-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: IN intervention group: 500mg L- carnitine, two times a day, as well as recommendation for exercise, weight loss and low fat diet, for six months. Intervention 2: Contol group: recommen
Treatment - Drugs
IN intervention group: 500mg L- carnitine, two times a day, as well as recommendation for exercise, weight loss and low fat diet, for six months
Contol group: recommendations for exercise, weight loss, and low fat diet for 6 months

Sponsors

Gasrtoenterology Research Centre Of Imam Reza Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: serum level of alanin aminotranspherase and aspartat aminotranspherase more than 40mg, ultrasonograghy evidences of fatty liver Exclusion criteria: overt diabetes, TG serum over 500mg, other causes of increasing liver enzymes such as viral infections, hemochromatosis , Wilson’s disease, autoimmune diseases, drinking (20 and 10 grams per day for men and women, respectively)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum level of alanine aminotransferase. Timepoint: Before intervention and six months after initiation of the intervention. Method of measurement: measuring serum level.

Secondary

MeasureTime frame
Serum level of aspartate aminotransferase. Timepoint: Before intervention and six months after initiation of the intervention. Method of measurement: by serum level measurement.;Fatty liver grading. Timepoint: befor intervention and six months after initiation intervention. Method of measurement: by ultasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezo Judaki

Tabriz University of Medical Sciences

JUDAKIA@tbzmed.ac.ir+98 41 1337 4290

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026