Skip to content

analgesic effect of ketamine in painful ophthalmic surgery

Analgesic effect of low dose- ketamine during anesthesia induction in 18-80 years pateint under surgery :Strabismus,Retinal Detachment,Keratoplasty

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201102235889N1
Enrollment
88
Registered
2011-12-15
Start date
2010-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: pain. Condition 2: Nausea and vomiting. Ocular pain Nausea and vomiting

Interventions

Intervention 1: Intervention:ketamine,0.5mg/kg during anaesthesia induction received intravenous. Intervention 2: control:normal salin, 0.5mg/kg during anaesthesia induction received intravenous.
Treatment - Drugs
Placebo
Intervention:ketamine,0.5mg/kg during anaesthesia induction received intravenous
control:normal salin, 0.5mg/kg during anaesthesia induction received intravenous

Sponsors

no sponsor
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:every women and men under surgery of Strabismus,Retinal Detachment,Keratoplasty .Exclusion criteria:every women and men under surgery of Strabismus,Retinal Detachment,Keratoplasty less than 18 years and older than 80years;have contraindication of ketamine for exp:increased ICP and IOP.Ischemic heart aneurysms.Psychiatric disease such as schizophrenia.open eye injury;addict to drugs;ASAof patient are not 1 and2;any changese in anesthetic plan that cause the use of drugs other than usual;any changese in surgical plan that cause changese in anesthetic plan;any changese in conditions of during surgery that cause changes in anesthesia drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The intensity of pain. Timepoint: after the patient's full consciousness in recovery. Method of measurement: according on VAS(0-10).;The intensity of nausea. Timepoint: after the patient's full consciousness in recovery. Method of measurement: according on VAS(0-10).;Vomiting frequency. Timepoint: in recovery if there is vomiting. Method of measurement: counting vomiting frequency in recovery.

Secondary

MeasureTime frame
Maxium of anasthetic drug. Timepoint: per 5 minutes until maxium 150microgeram per kg per minutes. Method of measurement: microgeram per kg per minutes untill reaching to 80-100% systolic BloodPressure before surgery.;Maxuim of analgesic during operation. Timepoint: per 10 minutes. Method of measurement: microgeram per kg untill reaching to 80-100% systolic BloodPressure before surgery.;Time interval between end of surgery till extubation. Timepoint: end of surgery till extubation. Method of measurement: Presence of spontaneous breathing of pationt with The minimum of normal tidal volume.;Analgesic requirement in recovery. Timepoint: after the patient's full consciousness in recovery. Method of measurement: microgeram per kg if VAS=4.bigger than4.;Period of time staying in recovery. Timepoint: when paition discharge of recovery. Method of measurement: acourding on patient's conditions of discharge in terms of minutes.;The duration of surgery. Timepoint: time of starting surgery till end of surgery. Method of measurement: in terms of minutes.;Mean blood pressure. Timepoint: per 5 min. Method of measurement: in terms of mmhg by blood pressure monitoring device.;Pulse. Timepoint: per 5 min. Method of measurement: per minutes by pulse monitoring device.;Age. Timepoint: before surgery write in Questionnaire. Method of measurement: years.;Sex. Timepoint: before surgery write in Questionnaire. Method of measurement: female-male.;Weight. Timepoint: before surgery write in Questionnaire. Method of measurement: kg-by Balance.;Underlying disease. Timepoint: before surgery write in Questionnaire. Method of measurement: Underlying disease:have.not have.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Abdollahi

Islamic Azad Medical University of Najafabad

mitra.abdolahi@Gmail.com+98 983312291111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026