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Comparison of the efficacy of oral fluconazole and oral Terbinafine in the treatment of moderate to severe seborrheic dermatitis

Comparison of the efficacy of oral fluconazole and oral Terbinafine in the treatment of moderate to severe seborrheic dermatitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201102205871N1
Enrollment
64
Registered
2013-02-05
Start date
2008-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seborrhoeic dermatitis. Seborrhoeic dermatitis

Interventions

Intervention 1: Fluconazole 300 mg weekly for four weeks. Intervention 2: Terbinafine 250 mg daily for four weeks.
Treatment - Drugs
Fluconazole 300 mg weekly for four weeks
Terbinafine 250 mg daily for four weeks

Sponsors

Gilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Patients with moderate to severe seborrheic dermatitis¸ filling the consent form,no previous treatment history at least 2 weeks before entering the study such as steroids, antifungal agents. Exclusion criteria:Lactation ¸ pregnancy ¸ no pervious diseases such as renal and liver failure, psoriasis, documented human immunodeficiency virus infection and/or sensitivity to fluconazole and terbinafine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
SDASI (Seborrheic dermatitis area severity index). Timepoint: weeks 4 , 6. Method of measurement: Determine severity of disease by examiner according to SDASI.;Itch. Timepoint: 4 weeks later and 6 weeks later. Method of measurement: subjective.

Secondary

MeasureTime frame
Side effects. Timepoint: at first,two and four weeks after treatment. Method of measurement: history,physical exam, laboratory tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Monadi Nori MD

Gilan University of Medical Sciencse

hamedmonadinori@yahoo.com+98 13 1554 1001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026