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The Treatment of Hemodialysis Patients' Anemia

The Effect of Intravenous and Oral Iron Administration on Responsiveness to Synthetic Erythropoietin in Hemoglobin Increase of Hemodialysis Patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201102195864N1
Enrollment
42
Registered
2011-08-29
Start date
2010-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iron Deficiency Anaemia. Other iron deficiency anaemias, Iron deficiency anaemia, unspecified

Interventions

Intervention 1: Intervention group: 100 mg intravenous Venofer, three times weekly at the end of each dialysis sessions for seven weeks. Intervention 2: Control group: Ferrous Sulfate tablet 50 mg dai
Treatment - Drugs
Intervention group: 100 mg intravenous Venofer, three times weekly at the end of each dialysis sessions for seven weeks
Control group: Ferrous Sulfate tablet 50 mg daily, for seven weeks

Sponsors

Vice chancellor for research, Golestan Medical Sciences University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Receiving hemodialysis therapy for at least 6 months; having dossier in hemodialysis ceneter; three time hemodialysis weekly and four hours for each session; hemoglobin less than 10 g/dl; history of seven weeks treatment with subcutaneous erythropoietin (2000 units, three times weekly at the end of each dialysis sessions). Exclusion criteria: Bone marrow malignancy; evidence of chronic infection; evidence of significant bleeding (decrease in Hb level > 2g/dL during the past 3 months); hemoglobinopathies; myelodysplastic syndrome.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hemoglobin. Timepoint: Pre and Post of Intervention. Method of measurement: Blood Exam.;Ferrtin. Timepoint: Pre and Post of Intervention. Method of measurement: Blood Exam.;Total Iron Bonding Capasity. Timepoint: Pre and Post of Intervention. Method of measurement: Blood Exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Reza Shariati

Golestan Medical Sciences University

shariati1382@yahoo.com+98 17 1442 6900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026