Effect of local haemostasis in patients taking warfarin

Effect of gelatin sponge and Tranexamic acid M.rines in prevention of bleeding after dental extraction in patients taking warfarin

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201102065565N2

Enrollment

Registered

2011-03-11

Start date

2008-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemorrhagic disorder due to circulating anticoagulants. Haemorrhagic disorder due to circulating anticoagulants

Interventions

Intervention 1: washing the extraction region with Tranexamic acid Ampule 4.8% for 2 days, 4 times in each day, for 2 minutes. Intervention 2: Placing a Gelatin Sponge in extraction region. Interventi

washing the extraction region with Tranexamic acid Ampule 4.8% for 2 days, 4 times in each day, for 2 minutes

Placing a Gelatin Sponge in extraction region

No intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: INR between 2 and 4, consumption of warfarin Exclusion criteria: consumption of NSAID before extraction, interrupting warfarin consumption before extraction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Active bleeding. Timepoint: after 1 hour and after 24 hours. Method of measurement: observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Peymani Mojaver

Faculty of Dentistry

a_peymani@rums.ac.ir+98 39 1822 0031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026