multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: control group: 1 capsule/day including placebo. Intervention 2: Q10 supplement (500mg/day) for 90 days.
Placebo
Treatment - Drugs
Q10 supplement (500mg/day) for 90 days
control group: 1 capsule/day including placebo
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 51 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 18-51 years, able to provide informed consent and diagnosed with relapsing remitting MS. Exclusion criteria: MS exacerbation during the study, systemically administered corticosteroids during the study , pregnant or breast-feeding , other significant health problem (e.g. active coronary heart disease, liver disease, pulmonary disease, diabetes mellitus and other autoimmune disease) that might increase the risk of subject experiencing adverse events. Consumption of vitamin, mineral and antioxidant supplement 30 days before study entry, Any condition which would make the subject, in the opinion of the investigator, unsuitable for the study and compliance less than 70%.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of serum MDA (malondialdehyde) concentration. Timepoint: 12 week. Method of measurement: Spectrophotometry.;Increase of glutathione peroxidase. Timepoint: 12 week. Method of measurement: Spectrophotometry.;Increase of SOD (superoxide dismutase). Timepoint: 12 week. Method of measurement: Spectrophotometry.;TAC (total antioxidant capacity). Timepoint: 12 week. Method of measurement: colorimetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Shahriar Eghtesadi
School of Health, Iran University of Medical Sciences
Outcome results
None listed