Study on the antimutagenicity effects of Vitamin-E in hospital nursing personals and control group using Ames assay and Comet assay

Assessing the antimutagenicity effects of oral Vitamin-E in hospital nursing personals and control group using Ames and Comet assay

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201101305710N4

Enrollment

Registered

2011-05-30

Start date

2011-04-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antimutagenicity effects of Vitamine E. Deficiency of vitamin E

Interventions

200mg/day of vitamin E for fifteen days.

Treatment - Drugs

200mg/day of vitamin E for fifteen days

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The age range of 20-60, agree to participate. Exclusion criteria: smoking, Vitamin-E consumption before 24h of entrance to study, over than eight hours of daily work.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Extracting of mutagenic compounds from urine sample. Timepoint: At the beginning and end of study. Method of measurement: Comet assay & Ames assay.	—

Secondary

Measure	Time frame
Nucleolus length in urine epithelial cells-Ratio (colony counts). Timepoint: At the beginning and end of study. Method of measurement: Urine mutagenicity activity will be evalued by Ames assay & Comet assay.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Rezaei Basiri

Tabriz University of Medical Sciences

basiri@razi.tums.ac.ir , mrb_pharma83@yahoo.com+98 41 1334 1315

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026