Condition 1: End-stage renal disease. Condition 2: Diabetes mellitus. End stage renal disease Diabetes mellitus due to underlying condition with diabetic chronic kidney disease
Conditions
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Number of hemodialysis sessions: 3 times per week At least 3 months of hemodialysis history Patients with type 2 diabetes Ability and willingness to collaborate on the project Age 70 – 40 years
Exclusion criteria
Exclusion criteria: Having an underlying disease (heart failure, acute liver disease, thyroid disease, and malignancy) Taking egg white supplements before entering the study Smoking, alcohol and hookah use Use of steroidal and nonsteroidal anti-inflammatory drugs Severe/allergic reaction to supplement, placebo, and cocoa powder Conditions such as uncontrolled high blood pressure or severe electrolyte imbalances that can interfere with the results of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nutritional status. Timepoint: At the beginning of the study and 8 weeks after the start of the intervention. Method of measurement: Calculate Body mass index and weight.;Dietary macronutrient composition. Timepoint: At the beginning of the study and 8 weeks after the start of intervention. Method of measurement: These individuals complete the International Physical Activity Questionnaire and a 24-hour diary for 3 days (2 non-dialysis days and 1 hemodialysis day), and their dietary intake information, such as macronutrient percentage and total calories, is calculated using the Nutritionist IV software.;Serum potassium, phosphorus, and sodium levels. Timepoint: At the beginning of the study and 8 weeks after the start of the intervention. Method of measurement: For biochemical indicators, 5 cc of venous blood samples will be taken from 44 patients at the beginning and end of the intervention after 12 hours of fasting. Then, using serum and whole blood samples, the levels of sodium, phosphorus, and potassium will be measured with a kit.;Total antioxidant capacity, Malondialdehyde, and superoxide dismutase. Timepoint: At the beginning of the study and 8 weeks after the start of the intervention. Method of measurement: At the beginning and end of the intervention, after 12 hours of fasting, 5 cc of venous blood samples will be taken from 44 patients who met the study inclusion criteria. Then, using serum and whole blood samples, we will measure the total antioxidant capacity, Malondialdehyde, and superoxide dismutase with the kit.;Sleep quality. Timepoint: At the beginning of the study and 8 weeks after the start of the intervention. Method of measurement: At the beginning and end of the intervention, 44 individuals who met the study entry criteria will complete the Pittsburgh Sleep Quality Index questionnaire, and by answering these questions and considering the differences before and after the intervention, the effect of egg white supplementation on the patients' slee | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood lipids. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: For biochemical indicators, 5 cc of venous blood samples will be taken from 44 patients at the beginning and end of the intervention after 12 hours of fasting. Then, using serum and whole blood samples, total cholesterol, high density lipoprotein, and triglyceride levels will be measured with a kit. Low density lipoprotein will be calculated using the Fried Ewald formula.;Blood sugar. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: For biochemical indicators, 5 cc of venous blood samples will be taken from 44 patients at the beginning and end of the intervention after 12 hours of fasting. Then, using serum and whole blood samples, fasting blood sugar levels will be measured with a kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Tarighat Esfanjani
Tabriz University of Medical Sciences
Outcome results
None listed