patients after kidney transplantation. Kidney transplant status
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: Curcumin capsules, one capsule containing 500 mg of curcumin (C3 complex, Sami Labs Ltd., Indi) daily with 5 mg of piperine (black pepper extrac
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age range 18-60 years People receiving kidneys from a deceased donor Complete and informed consent to participate in the research project People who do not have other diseases that increase oxidative stress, such as inflammatory bowel disease, liver cirrhosis, tumors and cancer People who only had a kidney transplant Do not take curcumin, turmeric and omega-3 supplements, vitamin E and C supplements within one month before the start of the study Do not take antiepileptic drugs within a month before the start of the study
Exclusion criteria
Exclusion criteria: People with cognitive disorders such as Alzheimer's
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of viral infections. Timepoint: During the study. Method of measurement: Diagnosis by the treating physician.;Blood sugar. Timepoint: At the beginning of the study and at the end of the study. Method of measurement: Biochemical testing.;Lipid profile. Timepoint: At the beginning of the study and at the end of the study. Method of measurement: Biochemical testing.;Blood pressure. Timepoint: At the beginning of the study and at the end of the study. Method of measurement: Biochemical testing.;Glomerular filtration rate. Timepoint: At the beginning of the study and at the end of the study. Method of measurement: Biochemical testing.;Delay graft function. Timepoint: From the beginning of the study to the end of the first week. Method of measurement: Need dialysis during the first week after transplantation.;Slow graft function. Timepoint: From the beginning of the study to the end of the tenth day. Method of measurement: Serum creatinine greater than 2.5 mg/dL on day 10 after transplantation.;Occurrence of acute graft rejection. Timepoint: From the beginning of the study to the end of the study. Method of measurement: Permanent return to dialysis, re-transplantation or death with an active transplant. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Beginning and end of the study. Method of measurement: With minimal clothing and without shoes and using Seca scales with an accuracy of 0.1 kg.;Height. Timepoint: Beginning and end of the study. Method of measurement: Shoeless by the meter mounted to the wall with an accuracy of 0.1 cm.;Waist circumference. Timepoint: Beginning and end of the study. Method of measurement: In the middle of the area between the lowest rib and the highest part of the pelvis at the end of natural exhalation using an inelastic tape measure without pressure on the body surface.;Length of hospital stay. Timepoint: during study. Method of measurement: Number of hospitalization days.;Leukopenia. Timepoint: Beginning and end of the study. Method of measurement: By counting the WBC.;Thrombocytopenia. Timepoint: Beginning and end of the study. Method of measurement: With platelet count less than 150,000 per microliter.;Neutropenia. Timepoint: Beginning and end of the study. Method of measurement: With a neutrophil count of less than 1500 per microliter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Tarighat Esfanjani
Tabriz University of Medical Sciences
Outcome results
None listed