type 2 diabetes. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: About 120 g fortified whole bread by whey protein concentrate per day for 90 days. Intervention 2: Control group: About 120 g whole bread per day for 90 days.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: Willingness to cooperation Women with type 2 diabetes mellitus Women aged 25-55 years glucose lowering tablets usage BMI= 25-35 kg/m2 GFR > 60 ml/min
Exclusion criteria
Exclusion criteria: Unwillingness to cooperation Patients with inflammatory, immunologic, psychologic, pulmonary, and neoplastic diseases Patients with renal, hepatic, and thyroid disorders Supplement intake Use of corticosteroids, non-steroidal anti-inflammatory, and hormonal drugs Change in type or dosage of used drugs during the study Change in diet and physical activity during the study Tobacco use Use of insulin Special physiologic conditions such as pregnancy, lactation, and menopause Patients with malabsorption diseases such as sprue and Crohn's disease Allergy or intolerance to milk components
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Blood Glucose. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Enzymatic by commercial kits.;Insulin. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: ELISA.;Hemoglobin A1C. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: ELISA with commercial kits.;HOMA-IR. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Calculation.;Triglyceride. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Enzymatic.;HDL-Cholesterol. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Enzymatic.;MDA. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: spectrophotometry.;TAC. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: spectrophotometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Pressure. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Digital Barometer.;Weight. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Scale.;Body Mass Index (BMI). Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Computing.;Body fat percent. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Bio impedance set.;Waist circumference. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: measurement by meter.;Hip circumference. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: measurement by meter.;WHR. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Computing.;Appetite. Timepoint: Before the intervention and 90 days after the start of the intervention. Method of measurement: Appetite Assessment Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Tarighat-Esfanjani
Tabriz University of Medical Sciences
Outcome results
None listed