Anxiety. Phobic anxiety disorder of childhood
Conditions
Interventions
Intervention 1: InterventionGroup B (Midazolam-Hydroxyzine): in this group, Hydroxyzine is administered with a dose of 1mg/kg at first, after 30 minutes Midazolam (0.5 mg/kg in mixture with the same v
Treatment - Drugs
InterventionGroup B (Midazolam-Hydroxyzine): in this group, Hydroxyzine is administered with a dose of 1mg/kg at first, after 30 minutes Midazolam (0.5 mg/kg in mixture with the same volume of 10% sug
Intervention group C (Oral Meperidine-Hydroxyzine): in this group both meperidine (2mg/kg) and hydroxyzine (1mg/kg) are administered simultaneousnessly 1 hour before treatment
Control Group (submucosal injection of meperidine-Hydroxyzine): in this group, Hydroxyzine (1mg/kg) is administered one hour before treatment. After 30 minutes of hydroxyzine administration, meperidin
Sponsors
Dental Research Center, Shahid Beheshti Dental School
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 2-6 years; Behavior: Negative or completely negative according to Frankl rating scale; Health status: ASA I; should have at least 3 consecutive similar treatment sessions. Exclusion criteria: history of allergic reactions to Benzodiazepines or any other drug used in the study; Previous complications with general anesthesia in patient or family; Hyper trophic adenoids in a manner that occupied more than 50% of pharyngeal space (Brodsky 2+>); Sleep apnea.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleepness. Timepoint: Once(at the beginning of the treatment). Method of measurement: Observation.;Movement. Timepoint: During the process of treatment. Method of measurement: Observation.;Crying. Timepoint: During the process of treatment. Method of measurement: Observation.;Overall behavior. Timepoint: During the process of treatment. Method of measurement: Observation.;Fear of Dentistry. Timepoint: Before treatment and after the final session. Method of measurement: questionnaire.;Recovery time. Timepoint: After treatment completion. Method of measurement: Observation.;Respiratory Rate. Timepoint: At the beggining of the study and then every 15 minutes. Method of measurement: Monitoring.;Blood Pressure. Timepoint: At the beggining of the study and then every 15 minutes. Method of measurement: Monitoring.;Oxygen Saturation. Timepoint: At the beggining of the study and then every 15 minutes. Method of measurement: Monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions. Timepoint: During and after treatment. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMs Asgari
Shahid Beheshti Dental school
Outcome results
None listed