POLY CYSTIC OVARIAN SYNDROME. Sclerocystic ovary syndrome Stein-Leventhal syndrome
Conditions
Interventions
Intervention 1: Intervention group 1 : In the fixed group , on day 3 of menstruation, gonadotropin stimulation with 150 IU subcutaneous of rFSH is initiated, Then Cetrotide 0.25 mg daily subcutaneou
Treatment - Drugs
Intervention group 1 : In the fixed group , on day 3 of menstruation, gonadotropin stimulation with 150 IU subcutaneous of rFSH is initiated, Then Cetrotide 0.25 mg daily subcutaneous is administrat
Group 2( flexible ):Third day of menstrual bleeding, gonadotropin 150IU rFSH (Gonalf ) is began daily subcutaneously.
Then if there is a follicle = 12 mm ,Cetrotide 0.25 mg is administered subcutan
Sponsors
Tehran University of Medical SciencesVice-chancellor of research,
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : infertile patients with poly cystic ovary syndrome;20-40 years old Body mass index BMI 20-30 kg/m2 Exclusion criteria: endometriosis;ovarian cysts; pelvic neoplasia of the uterine and ovarian ; endocrine disorders (disorders of tyroid , prolactin); male factor infertility; blocked fallopian tubes in HSG, FSH levels on the 3th day of menestration >12miu/ml, previous OHSS; history of RIF (RECURRENT IMPLANTATION FAILURE)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate. Timepoint: 4-6weeks after emberyo transfer. Method of measurement: the presence of gestational sac with fetal heart beat detectionat 6–7 weeks of gestation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dose of cetrotide. Timepoint: at the end of controlled ovarian stimulation period. Method of measurement: dose of administration of Cetrotide.;Duration of administration of Cetrotide. Timepoint: at the end of controlled ovarian stimulation period. Method of measurement: days of administration of Cetrotide.;Ongoing pregnancy. Timepoint: the presence of gestational sac with fetal heart beat detection at 12 w of gestation. Method of measurement: the presence of gestational sac with fetal heart beat detection at 12 w of gestation.;Duration of administration of rFSH. Timepoint: at the end of controlled ovarian stimulation period. Method of measurement: days of administration of rFSH.;Dose of rFSH. Timepoint: at the end of controlled ovarian stimulation period. Method of measurement: dose of administration of rFSH.;Hospitalization rate due to OHSS. Timepoint: at the controlled ovarian stimulation period -UNTIL 4 weeks after pregnancy. Method of measurement: days of hospitalization due to OHSS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTahereh Behroozi lak
Vali-e-Asr reproductive HealthnResearch center
Outcome results
None listed