The Treatment Effect of Nonsurgical Periodontal Therapy for Eradication of Helicobacter Pylori Infection Following Systemic Therapy

Comparing the Systemic Therapy in patients with dyspepsia with and without Periodontal Therapy for Eradication of Helicobacter Pylori Infection.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110109005570N9

Enrollment

Registered

2021-04-14

Start date

2016-09-22

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peptic ulcer or dyspepsia. Acute peptic ulcer

Interventions

Intervention 1: Triple therapy (G +O +tp)include pantoprazol 40mg q2d,Bismuth sub-citrate 240mg q2d,amoxycillin 1gr q2d, Clarithromycin 500 for 14 days.. non surgical treatment consist of oral hygiene

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Peptic ulcer or dyspepsia positive for helicobacter pylori infection based on stool helicobacter pylori antigen test evaluation or serology

Exclusion criteria

Exclusion criteria: Suffering from MALT Zolinger Elison syndrome GI tract cancer Liver and kidney disease Tacking antibiotics or probiotic in past 4 weeks or any contraindication for tacking medicinal diet Immunologic disease Pregnancy History of upper GI tract surgery History of eradication of Helicobacter pylori infection History of tacking PPI Do not take medication regularly(20% or more) Serious side effect as a result of tacking medication Request a patient to leave the study Failure for oral hygiene.

Design outcomes

Primary

Measure	Time frame
The presence of H. pylori in GI tract and its eradication. Timepoint: Base line(before treatment), 1 months after treatment. Method of measurement: Stool H. pylori antigen test.;Presence of H. pylori in dental plaque. Timepoint: Base line(before treatment). Method of measurement: Rapid Urease Test.	—

Secondary

Measure	Time frame
Probing depth. Timepoint: Base line(before treatment),1 months after treatment. Method of measurement: Probing by Williams prob, from gingival margin to depth of pocket.;Plaque index. Timepoint: Base line(before treatment) and 1 months after treatment. Method of measurement: Plaque index of silness and loe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShirin Rostami

Esfahan University of Medical Sciences

shirinrostami.dnt@gmail.com+98 31 3792 5570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026