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Effect of Atorvastatin gel on clinical and histological parameters in socket preservation

Determining the effects of using 1.2% Atorvastatin gel with absorbable membrane on clinical and histological parameters in socket preservation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110109005570N11
Enrollment
15
Registered
2021-07-22
Start date
2021-07-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

socket preservation. Partial loss of teeth, unspecified cause

Interventions

Intervention 1: Intervention group: extraction of tooth and placing atorvastatin gel in socket and covering it with claprotect membranes made by Bottis company and then suturing on it. Intervention 2:

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patient with healthy systemic condition Single-rooted or double-rooted teeth Presence of sound buccal and lingual plates after tooth extraction Presence of a minimum of 10 mm vertical bone height without invading the adjacent critical structures,

Exclusion criteria

Exclusion criteria: Allergy to collagen membrane Severe untreated periodontitis Acute infection or pus at the extraction site

Design outcomes

Primary

MeasureTime frame
Length of socket. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Periodontal probe.;Width of socket. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Periodontal probe.;Width of keratinized gingiva. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Periodontal probe.;Thickness of gingiva. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Periodontal probe.;Percent of ossification of alveolar socket. Timepoint: 2 months after the intervention. Method of measurement: Histological evaluation.;Thickness of new trabecula. Timepoint: 2 months after the intervention. Method of measurement: Histological evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParichehr Behfarnia

Esfahan University of Medical Sciences

behfarnia@dnt.mui.ac.ir+98 31 3792 5559

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026