Evaluation of the effect of vitamin E in chronic periodontitis

Comparison of the effectiveness of vitamin E supplementation in the treatment of patients with chronic periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110109005570N10

Enrollment

Registered

2021-07-21

Start date

2019-12-06

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: Scaling and root planing with ultrasonic device(cavitron), Prescribe 200 units of vitamin E capsules once a day for two months. Intervention 2: Control group: Scali

Eligibility

Sex/Gender

All

Age

25 Years to 70 Years

Inclusion criteria

Inclusion criteria: patients with generalized chronic mild to moderate periodontitis and clinical attachment loss between 1 and 5 mm

Exclusion criteria

Exclusion criteria: patients with systemic disease or unwillingness to continue the study

Design outcomes

Primary

Measure	Time frame
Pocket depth. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by periodontal probe.;Clinical attachment level. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by periodontal probe.;Total anti oxidant capacity of saliva. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by Zellbio’s TAC Kit.	—

Measure

Time frame

Pocket depth. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by periodontal probe.;Clinical attachment level. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by periodontal probe.;Total anti oxidant capacity of saliva. Timepoint: At the beginning of the study (before the intervention) and 2 months after scaling and taking vitamin E capsules. Method of measurement: by Zellbio’s TAC Kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactParichehr Behfarnia

Esfahan University of Medical Sciences

Dr.pbehfarnia@gmail.com+98 31 3792 5559

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026