The evaluation of the effect of adding Magnesium Sulfate to intrathecal Marcain to control shivering during cesarean section surgery

The evaluation of the effect of adding Magnesium Sulfate to intrathecal Marcain to control shivering during cesarean section surgery with spinal anesthesia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201101055182N4

Enrollment

Registered

2011-02-02

Start date

2011-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering during cesarean section surgery. Hypothermia following anesthesia

Interventions

Intervention 1: The magnesium sulfate group receive 2 cc marcain 0.5% (10 mg), 0.5 cc magnesium sulfate 5% (25 mg). Intervention 2: The control group receive 2 cc marcain 0.5% , 0.5 cc normal saline.

Treatment - Drugs

Placebo

The magnesium sulfate group receive 2 cc marcain 0.5% (10 mg), 0.5 cc magnesium sulfate 5% (25 mg)

The control group receive 2 cc marcain 0.5% , 0.5 cc normal saline

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA physical status I or II, age 18-35 years old, signing consent to participate in the study. Exclusion criteria: Patients not willing participate in project, pre-eclampsia, lidocaine and magnesium sulfate allergy, drug and alcohol abuse, neuropathy, infection in block site, respiratory distress, coagulopathy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Central body temperature. Timepoint: Before spinal block, immediately after spinal block, each 30 mine during 1 hour after admission to recovery. Method of measurement: Thermometer.;Systolic arterial pressure. Timepoint: 5 minutes for 15 minutes then each 10 minutes til the end of recovery. Method of measurement: Sphygmomanometer.;Heart rate. Timepoint: 5 minutes for 15 minutes then each 10 minutes til the end of recovery. Method of measurement: Rate/min.;Sedation. Timepoint: Before spinal block, immediately after spinal block, each 30 minutes during 1 hour after admission to recovery. Method of measurement: Basd on Ramsy criteria.	—

Measure

Time frame

Central body temperature. Timepoint: Before spinal block, immediately after spinal block, each 30 mine during 1 hour after admission to recovery. Method of measurement: Thermometer.;Systolic arterial pressure. Timepoint: 5 minutes for 15 minutes then each 10 minutes til the end of recovery. Method of measurement: Sphygmomanometer.;Heart rate. Timepoint: 5 minutes for 15 minutes then each 10 minutes til the end of recovery. Method of measurement: Rate/min.;Sedation. Timepoint: Before spinal block, immediately after spinal block, each 30 minutes during 1 hour after admission to recovery. Method of measurement: Basd on Ramsy criteria.

—

Primary

Measure	Time frame
Shivering. Timepoint: During 90 minutes after spinal block in 0, 5,10,15,20,30,40,50,60 and 90 minutes. Method of measurement: None, Mild, Moderate, Severe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Feiz MD

Tehran University of Medical Sciences and Health Services

h.faiz@iums.ac.ir+98 21 4481 9954

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026