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Comparison of Hemodynamic Changes in Administration of Ondansetron and Metoclopramide in Preventing Post Operative Nausea and Vomiting after Strabism Surgery

Comparison of Hemodynamic Changes in Administration of Ondansetron and Metoclopramide in Preventing Post Operative Nausea and Vomiting after Strabism Surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201101052496N5
Enrollment
96
Registered
2011-02-19
Start date
2009-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabism. Strabism, unspecified

Interventions

Intervention 1: Metoclopramide (Dopamine receptor antagonist used for the treatment of nausea and vomiting) 150?g/kg administered intravenously(at one time) five minutes before induction of general an
Prevention
Metoclopramide (Dopamine receptor antagonist used for the treatment of nausea and vomiting) 150?g/kg administered intravenously(at one time) five minutes before induction of general anesthesia after r
Ondansetron (5HT3 antagonist anti-emetic used for the treatment of nausea and vomiting) 50?g/kg administered intravenously(at one time) five minutes before induction of general anesthesia after routin

Sponsors

Research Vice chancellor of Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with average age of 6-12y/o, ASA (American Society of Anesthesiologists) physical status I and II candidated for strabism surgery with general anesthesia Exclusion criteria: The patients who received antiemetics during previous 24 hours, the patients suffering from liver, renal, gastrointestinal disorders and motion sickness

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea. Timepoint: After 0, 2, 6 and 24 hours of surgury. Method of measurement: Zero for not having nausea - 1, for mild nausea- 2, for moderate nausea and 3 for sever nausea.

Secondary

MeasureTime frame
Vomiting. Timepoint: After 0, 2, 6 and 24 hours of surgury. Method of measurement: Zero for the patients not experiencing vomiting, 1 for the little vomiting, 2 for vomiting gastric contents and 3 for vomiting food particles.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Parvar Hassanzadeh Salmasi

Tabriz University of Medical Sciences

Parvar.88@Gmail.com+98 41 1336 7494

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026