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Dextromethorphan and posttansillectomy pain

Evaluation of Preemptive analgesia with dextromethorphan gurgling during tonsillectomy operation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201101035536N1
Enrollment
40
Registered
2011-05-24
Start date
2010-05-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post tonsilectomy pain condition. Hypertrophy of tonsils with hypertrophy of adenoids

Interventions

Intervention 1: First intervention group: Syrup containing 45 mg dextrometorphan 90 minutes before entering to operating room. Intervention 2: Second intervention group: gurgle of 45 mg dextrometorph
Treatment - Drugs
Placebo
First intervention group: Syrup containing 45 mg dextrometorphan 90 minutes before entering to operating room.
Second intervention group: gurgle of 45 mg dextrometorphan syrup 60 seconds immediately before entering to operating room.
Control group: 60 minute before operatin, placebo same as volume of 45 mg dextromethorphan syrup ,vitamin-C syrup will beadmistered for patients.

Sponsors

Army University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: All 18-45 years age ASA I-II peoples who signed informed consent Exclusion criteria: Patients with any past history of chronic pain; opioid addiction and serious cardiac and renal or hepatic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post operation pain. Timepoint: Every six hours till 24 hours. Method of measurement: Visual Analog Scale.

Secondary

MeasureTime frame
Free pain periods. Timepoint: Every six hours till 24 hours. Method of measurement: Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026