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Investigating the effect of intravenous ondansetron on arterial blood pressure changes and heart rate in patient undergoing surgery with spinal anesthesia

Investigating the effect of intravenous ondansetron on arterial blood pressure changes and heart rate in patient undergoing inguinal hernia repair surgery with spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110103005536N10
Enrollment
130
Registered
2021-04-01
Start date
2021-04-18
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia.

Interventions

Intervention 1: Intervention group: After placing the patient on the operating table and before performing spinal anesthesia, systolic blood pressure, diastolic blood pressure, moderate blood pressure

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient is a candidate for spinal hernia repair surgery by spinal anesthesia The patient has consented to spinal anesthesia

Exclusion criteria

Exclusion criteria: The patient has a contraindication to spinal anesthesia. The patient has hypertension The patient has a history of heart disease The patient has a history of migraine The patient has a history of allergy to ondansetron The patient has a history of taking any medication that changes blood pressure or heart rate

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: Before, during and after spinal anesthesia. Method of measurement: NIBP (non invasive blood pressure) monitoring.;Diastolic blood pressure. Timepoint: Before, during and after spinal anesthesia. Method of measurement: NIBP (non invasive blood pressure) monitoring.;Mean arterial pressure. Timepoint: Before, during and after spinal anesthesia. Method of measurement: NIBP (non invasive blood pressure) monitoring.;Hearth rate. Timepoint: Before, during and after spinal anesthesia. Method of measurement: Patient's monitoring.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: After spinal anesthesia. Method of measurement: Clinical observation.;Chills. Timepoint: After the intervention. Method of measurement: Clinical observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammadreza Rafiei

Artesh University of Medical Sciences

mo_rafiei@armyums.ac.ir+98 21 8609 6350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026