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Comparison of Gentamicin and Mupirucine ointments on the rate of peritonitis and exit site infection in peritoneal dialysis

Comparison of Gentamicin and Mupirucine ointments on the rate of peritonitis and exit site infection in peritoneal dialysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201012282417N5
Enrollment
120
Registered
2011-01-25
Start date
2009-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease. End-stage renal disease

Interventions

Intervention 1: Gentamicin 0.1% ointment daily on the catheter exit site of peritoneal dialysis for 6 months. Intervention 2: Mupirocine 2% ointment daily on the catheter exit site of peritoneal dialy
Treatment - Drugs
Gentamicin 0.1% ointment daily on the catheter exit site of peritoneal dialysis for 6 months
Mupirocine 2% ointment daily on the catheter exit site of peritoneal dialysis for 6 months

Sponsors

Vice Chancellor for Research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age at least 18 years, at least 3 months on peritoneal dialysis, Satisfaction to participate in the study, lack of cutaneous hypersensitivity to gentamicin or Mupirocine ointments, Not receiving systemic antibiotics during the 30 days prior to the study Exclusion criteria: systemic antibiotic treatment during the study, changing in dialysis route, transplantation or death, no satisfaction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Rate of peritonitis. Timepoint: monthly. Method of measurement: clinical symptoms and direct inspection of dialysis fluid.

Secondary

MeasureTime frame
Raete of exit site infection. Timepoint: monthly. Method of measurement: clinical symptoms.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mojgan Mortazavi

Isfahan University of Medical Sciences

m_mortazavi@med.mui.ac.ir+98 31 1668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026