comparison of standard dose of human chorionic gonadotropin and human chorionic gonadotropin In combination with gonadotropin releasing hormone in IVF/ICSI cycles

comparison of ovulation triggering outcome using these two methods: standard dose of human chorionic gonadotropin and human chorionic gonadotropin In combination with gonadotropin releasing hormone in IVF/ICSI cycles

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101227005485N7

Enrollment

100

Registered

2019-07-18

Start date

2019-06-22

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility

Interventions

Intervention 1: Intervention group: 2500 unit human chorionic gonadotropin In combination with 0.2 miligram gonadotropin releasing hormone. Intervention 2: Control group: 10000 unit human chorionic go

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: women who are candidate of IVF/ICSI and have some risk of OHSS will be entered in the study.

Exclusion criteria

Exclusion criteria: every body who have diminished ovarian reserve. (AFC<4 or AMH<1)

Design outcomes

Primary

Measure	Time frame
Number and quality of resulted oocytes. Timepoint: the day of oocytes pick up. Method of measurement: microscopic evaluation.;Fertilization rate. Timepoint: 24 hours after intra-cytoplasmic sperm injection. Method of measurement: microscope.;Implantation rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: Measurement of beta-hCG.;Number and quality of embryos. Timepoint: after 24 hours, day 3 and day 5. Method of measurement: microscopic evaluation.	—

Measure

Time frame

Number and quality of resulted oocytes. Timepoint: the day of oocytes pick up. Method of measurement: microscopic evaluation.;Fertilization rate. Timepoint: 24 hours after intra-cytoplasmic sperm injection. Method of measurement: microscope.;Implantation rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: Measurement of beta-hCG.;Number and quality of embryos. Timepoint: after 24 hours, day 3 and day 5. Method of measurement: microscopic evaluation.

—

Secondary

Measure	Time frame
Ovarian hyperstimulation syndrome. Timepoint: the day of oocyte pick-up and a week later. Method of measurement: history, physical examination and laboratory tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazli Navali

Tabriz University of Medical Sciences

navalin@tbzmed.ac.ir+98 41 3554 1221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026