Female infertility. Female infertility
Conditions
Interventions
Intervention 1: Group 1 (Combined Treatment): This group undergoes ovarian stimulation with a combination of Clomiphene Citrate 50 mg (two tablets daily for 5 days) and Letrozole 2.5 mg (two tablets d
Sponsors
Vice chancellor for Research, Tabriz University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
No minimum to 42 Years
Inclusion criteria
Inclusion criteria: Infertile women under 42 years of age Willingness to participate in the study and signing an informed consent form Patients with ovarian reserve above 1
Exclusion criteria
Exclusion criteria: Existence of severe underlying diseases that affect fertility Use of medications that affect ovarian suppression in the past month Hyperlactinemia Primary ovarian insufficiency Hypothalamic amenorrhea Thyroid diseases Severe spermogram disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of oocytes retrieved. Timepoint: The ovulation day. Method of measurement: Microscopic examination.;Quality of retrieved oocytes. Timepoint: The ovulation day. Method of measurement: Microscopic examination.;Incidence rate of ovarian hyperstimulation syndrome (OHSS. Timepoint: 3 to 7 days after the injection of human chorionic gonadotropin (hCG). Method of measurement: Transvaginal ultrasound.;Fetal quality. Timepoint: Two days after embryo transfer. Method of measurement: Diagnosis of the embryo specialist according to embryological criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Serum level of hCG-ß.;Clinical pregnancy. Timepoint: 4 weeks after fetal transfer. Method of measurement: Vaginal ultrasound and see a pregnancy bag.;The ongoing pregnancy rate. Timepoint: By week 14 pregnancy. Method of measurement: Ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNazli Navali
Tabriz University of Medical Sciences
Outcome results
None listed