The comparison of drug and mechanical methods for cervical ripening before delivery

Efficacy and side effects of transcervical catheter and vaginal Misoprostol on cervical ripening

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201012225448N1

Enrollment

120

Registered

2011-05-04

Start date

2010-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ripening Of Cervix. Complications of labour and delivery

Interventions

Intervention 1: Misoprostol 25 microgram per 8 hour until 3 doses will be used in 60 patients with the cervix bishop score 3 or 4. Then duration time to reach 8 bishop score will be measured. Interv

Treatment - Other

Misoprostol 25 microgram per 8 hour until 3 doses will be used in 60 patients with the cervix bishop score 3 or 4. Then duration time to reach 8 bishop score will be measured.

On the other 60 ones with cervix bishop score of 3or4, transcervical catheter will be used. time of receiving to cervix bishop score of 8 will be evaluated.

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:gestatinal age over 37 weeks, singleton gestation,cephalic presentation, intact amnion sac,not contraindication of misoprostol use,first gravity ,3 to 4 bishop score Exclusion criteria:allergy to misoptostol,elective cesarean section,urgent delivery by c/s,IUGR,placenta previa,fetal bradycardia, placenta abruption,massive bleeding ,placenta previa and previous cesarean section.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ripening of cervix. Timepoint: in the time of intervention. Method of measurement: bishop score.	—

Secondary

Measure	Time frame
Meconium In Amnionic Fluid. Timepoint: at time of intervention. Method of measurement: Clinical.;Uterine Hyperstimulation. Timepoint: at time of intervention. Method of measurement: clinical.;Rupture of uterin. Timepoint: at time of intervention. Method of measurement: clinical.;Result in c/s. Timepoint: at time of intervention. Method of measurement: Clinical.;Fetal Bradycardia. Timepoint: In the time of intervention. Method of measurement: Clinical.	—

Measure

Time frame

Meconium In Amnionic Fluid. Timepoint: at time of intervention. Method of measurement: Clinical.;Uterine Hyperstimulation. Timepoint: at time of intervention. Method of measurement: clinical.;Rupture of uterin. Timepoint: at time of intervention. Method of measurement: clinical.;Result in c/s. Timepoint: at time of intervention. Method of measurement: Clinical.;Fetal Bradycardia. Timepoint: In the time of intervention. Method of measurement: Clinical.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Fatemeh Mallah

Tabriz University Of Medical Sciences

mallahf@tbzmed.ac.ir+98 41 1442 4423

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026