Comparison of effect of Epinephrine 1:1000 with Epinephrine 1:10000 in spinal anesthesia

The comparison of addition of epinephrine 1:1000 and 1:10000 to lidocaine and Fentanyl on paralysis and analgesia prolongation and hemodynamic changes (BP– HR) in spinal anesthesia in Cesarean Section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201012225445N1

Enrollment

Registered

2011-08-09

Start date

2011-02-14

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia during labor and delivery. Other complications of spinal and epidural anaesthesia during labour and delivery

Interventions

Intervention 1: Group A (control) : Lidocaine 5% , Fentanyl and Epinephrine 1:1000. Intervention 2: Group B (intervention) : Lidocaine 5% , Fentanyl and Epinephrine 1:10000.

Treatment - Drugs

Group A (control) : Lidocaine 5% , Fentanyl and Epinephrine 1:1000

Group B (intervention) : Lidocaine 5% , Fentanyl and Epinephrine 1:10000

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 20 to 35 years old pregnant who are candidate for cesarean section under spinal anesthesia Exclusion criteria: unsuccessful spinal anesthesia, level of anesthesia out of the T4 – T6, any type of incision except faneshtein, underlying diseases such as diabetes, hypertension or coagulopathy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: 1 - 3 - 5 - 10 - 15 min. Method of measurement: Sphygmomonometere.;Paralysis. Timepoint: Every 15 min. Method of measurement: Check list.;Heart rate. Timepoint: 1 - 3 - 5 - 10 - 15 min. Method of measurement: Pulse oxymeter.;Analgesia. Timepoint: Every 15 min. Method of measurement: Check list.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Arash Hamzei , anesthesiologist

Gonabad University of Medical sciences

arash_hamzei@gmu.ac.ir?arash_hamzei@yahoo.com+98 53 3722 4138

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026