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Comparison of Sublingual buprenorphine and intravenous morphine for postoperative analgesic effect hemodynamic changes, nausea & vomiting

Comparison of Sublingual buprenorphine and intravenous morphine for postoperative analgesic effect hemodynamic changes, nausea & vomiting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201012203305N2
Enrollment
100
Registered
2011-01-31
Start date
2010-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia in ASA ClassI, II. Other complications of anaesthesia

Interventions

Intervention 1: Sublingual buprenorphine 0.4mg as well as 6 ml N/S as placebo. Intervention 2: IV morphine 6mg in 3 min as well as a sublingual tab as placebo.
Prevention
Sublingual buprenorphine 0.4mg as well as 6 ml N/S as placebo
IV morphine 6mg in 3 min as well as a sublingual tab as placebo

Sponsors

Vice-chancellor for Research, Babol University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18-60 years old, ASA Class I, II, candidate for lower limbs orthopedic surgery, herniorraphy, or varicocelectomy Exclusion criteria: History of complications such as: respiratory, cardiovasculer diseases, hypertension, diabetes mellitus, or addiction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative analgesic effect. Timepoint: before intervention untill 12 hours after intervention. Method of measurement: Visual analogue pain score.;Hemodynamic changes. Timepoint: before intervention untill 12 hours after intervention. Method of measurement: Pulse Oxymeter , Sphigmo manometer.;Nausea & Vomiting. Timepoint: Before intervention untill 12 hour after intervention. Method of measurement: Visual - questional.

Secondary

MeasureTime frame
Oxygen saturation. Timepoint: 15, 30, 60 min after procedure, half an hour, before and after 2 and 12 hours. Method of measurement: pulse oximeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ebrahim Alijanpour

Babol University Of Medical Sciences

dralijanpour@yahoo.com+98 11 1223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026