Skip to content

Hemodynamic effects of Propofol-Fentanyl and Propofol-Lidocaine in patients undergoing endoscopy

Investigation of hemodynamic effects of two combinations of Propofol-Fentanyl and Propofol- Lidocaine in patients undergoing upper endoscopy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101220005426N11
Enrollment
198
Registered
2021-08-20
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper endoscopy.

Interventions

Intervention 1: The first intervention group: after receiving 0.05 mg / kg Midazolam and 40 mg / min Propofol maintenance, we give the first group 1 ug / kg Fentanyl (from Abu Reihan company) with the

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients undergoing upper endoscopy Patients aged 20 to 40 years

Exclusion criteria

Exclusion criteria: Addiction High blood pressure Hyperlipidemia Underlying disease, including thyroid disease, etc. Patients with G6PD disorder Myasthenia gravis methemoglobinemia Heart block Wolff-Parkinson-White syndrome Adams-Stokes syndrome Low blood potassium levels

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Checking of blood pressure once before drug administration and once after drug injection before endoscopy and then every 5 minutes until completion of work. Method of measurement: Patient monitoring system.;Heart rate. Timepoint: Checking of heart rate once before drug administration and once after drug injection before endoscopy and then every 5 minutes until completion of work. Method of measurement: Patient monitoring system.;Arterial blood oxygen saturation. Timepoint: Checking of arterial blood oxygen saturation once before drug administration and once after drug injection before endoscopy and then every 5 minutes until completion of work. Method of measurement: Patient monitoring system.;Respiratory rate. Timepoint: Checking of respiratory rate saturation once before drug administration and once after drug injection before endoscopy and then every 5 minutes until completion of work. Method of measurement: Patient monitoring system.;Gag reflex. Timepoint: During upper endoscopy. Method of measurement: Doctor checkup.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Ahmadinejad

Kerman University of Medical Sciences

mehdia50@gmail.com+98 34 3223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026