sexual hormone.
Conditions
Interventions
Intervention 1: 100 milligram Aspirin daily for 6 weeks. Intervention 2: One Placebo capsule daily for 6 weeks.
Treatment - Drugs
Placebo
100 milligram Aspirin daily for 6 weeks
One Placebo capsule daily for 6 weeks
Sponsors
Vive-chancellor for research,Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 45-80 years, not using NSAID drugs during past 3 months, not having menstruation cycle during the past 12 months, bilateral oophorectomy, hysterectomy without the bilateral oophorectomy with age more than 56 for smokers and age more than 54 years old for non-smokers, not using sexual hormones during the past 3 months Exclusion criteria:Taking NSAIDS or another inflammatory drugs, Inflammatory diseases, consuming of drugs that can alter the estradiol level for instance: inhibitor's aromotase enzyme, women who are candidate for surgery during the following 2-3 months, not willing to participate
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estradiol. Timepoint: 6 weeks. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| SHBG (sex Hormone Binding Glubolin). Timepoint: 6 weeks. Method of measurement: ELISA.;Testestrone. Timepoint: 6 weeks. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMania Radfar
Tehran University Of Medical Sciences
Outcome results
None listed