Skip to content

Effect of dexamethasone on nausea and vomiting

Prophylactic effect of dexamethasone on postoperative nausea and vomiting in patients under stapedectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201012133181N3
Enrollment
70
Registered
2012-02-28
Start date
2007-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Stapedectomy surgery. Condition 2: Nausea and vomiting. Nausea and vomiting

Interventions

Intervention 1: Dexamethone, 16mg, will be injected intravenously half an hour before surgery. Intervention 2: 4ml normal saline, as placebo, will be injected intravenously half an hour before surgery
Prevention
Placebo
Dexamethone, 16mg, will be injected intravenously half an hour before surgery.
4ml normal saline, as placebo, will be injected intravenously half an hour before surgery.

Sponsors

Vice Chancellor for Research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 62 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: adult patients undergoing stapedectomy surgery who were referred to ENT clinic of Amiralam hospital and classification of physical status (American society of Anesthesilogist) ASA class I or II component. Exclusion criteria: motion sickness; history of GI disorder; history of diabetes and history of antiemetic drugs to 48 hours before surgery; history of taking corticosteroids, and prior history of PONV during two weeks before.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea and Vomiting. Timepoint: 1-24 hour. Method of measurement: observation and questionary.

Secondary

MeasureTime frame
Vertigo. Timepoint: 1-24 hour. Method of measurement: questionary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Mokhtari

Otorhinolaryngology Research Center,Tehran University of Medical Sciences

zmokhtari@razi.tums.ac.ir+98 21 6676 0269

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026