The effect of norepinephrine and phenylephrine on maternal hemodynamic changes

Comparison of the effect of norepinephrine and phenylephrine on maternal hemodynamic changes after spinal anesthesia in cesarean section

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101213005381N15

Enrollment

Registered

2022-05-29

Start date

2022-05-31

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section. Complications of anesthesia during labor and delivery

Interventions

Intervention 1: Intervention group: After spinal anesthesia, prophylaxis injection of 10 micrograms of norepinephrine Intervention group. Intervention 2: Intervention group: After spinal anesthesia, p

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 18 to 35 years pregnant women Elective cesarean delivery American Society of Anesthesiologists Classification (ASA) 1 &2

Exclusion criteria

Exclusion criteria: American Society of Anesthesiologists Classification (ASA) > 3 Bradycardia Hypertension Use of anti hypertensive drugs Operation longer than 3 hours

Design outcomes

Primary

Measure	Time frame
Percentage of people with hypertension. Timepoint: Before spinal anesthesia once and then after spinal anesthesia once every 3 minutes until the baby leaves and then twice 10 minutes after delivery. Method of measurement: Monitoring of blood pressure, mm Hg.;Number of Heart rate. Timepoint: Before spinal anesthesia once and then after spinal anesthesia once every 3 minutes until the baby leaves and then twice 10 minutes after delivery. Method of measurement: Number per minute using pulse oximeter (Sazgan Gostar Company).	—

Measure

Time frame

Percentage of people with hypertension. Timepoint: Before spinal anesthesia once and then after spinal anesthesia once every 3 minutes until the baby leaves and then twice 10 minutes after delivery. Method of measurement: Monitoring of blood pressure, mm Hg.;Number of Heart rate. Timepoint: Before spinal anesthesia once and then after spinal anesthesia once every 3 minutes until the baby leaves and then twice 10 minutes after delivery. Method of measurement: Number per minute using pulse oximeter (Sazgan Gostar Company).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNadia Banihashem

Babol University of Medical Sciences

nbanihashem@mubabol.ac.ir+98 11 3233 8301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026