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Comparison of Intranasal versus Intravenous Pethidine for Pain Relief after Cesarean Section

Comparison of Intranasal versus Intravenous Pethidine for Pain Relief after Cesarean Section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201012122405N6
Enrollment
126
Registered
2011-01-02
Start date
2006-06-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of anaesthesia during pregnancy. Other complications of anaesthesia during pregnancy

Interventions

Intervention 1: Intravenous Pethidine (1mg/kg), Duration of treatment: single dose. Intervention 2: Intranasal Pethidine (1mg/kg), Duration of treatment: single dose.
Treatment - Drugs
Intravenous Pethidine (1mg/kg), Duration of treatment: single dose
Intranasal Pethidine (1mg/kg), Duration of treatment: single dose

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Parturients, ASA physical status I-II, scheduled for elective cesarean section, under general anesthesia Exclusion Criteria: suspicious to bleeding disturbances, allergy to meperidine, atopia, diabetes mellitus, presence of liver or kidney diseases, drugs abuse, hypertension of pregnancy, preeclampsia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: recovery room(0) ,0.5 , 1, 1.5, 2, 2.5, 3, 3.5 and 4 hours postoperative. Method of measurement: Visual Analogous Scale (VAS) and scoring from 0 to 10.

Secondary

MeasureTime frame
Systolic blood pressure. Timepoint: recovery room(0) ,0.5 , 1, 1.5, 2, 2.5, 3, 3.5 and 4 hours postoperative. Method of measurement: using mercury manometer.;Heart rate. Timepoint: recovery room(0) ,0.5 , 1, 1.5, 2, 2.5, 3, 3.5 and 4 hours postoperative. Method of measurement: Using EKG Monitoring.;Opioid consumption. Timepoint: recovery room(0) ,0.5 , 1, 1.5, 2, 2.5, 3, 3.5 and 4 hours postoperative. Method of measurement: mili gram of opioid.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mitra Jabalameli

Isfahan University of Medical Sciences

jabalameli@med.mui.ac.ir+98 31162555551532

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026