FindTrial
Sign In

Comparison of the results of adding ondansetron, dexmedetomidine and trinitroglycerine to lidocaine in the Bier technique on the properties of sensory, motor block and pain relief compared to the control group

Comparison of the results of adding ondansetron, dexmedetomidine and trinitroglycerine to lidocaine in the Bier technique on the properties of sensory, motor block and pain relief compared to the control group

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101211005362N32
Enrollment
120
Registered
2025-03-04
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb fractures. Fracture of upper limb, level unspecified

Interventions

Intervention 1: Control group: Lidocaine 0.5%, 3 mg/kg (maximum 200 mg) for IVRA. Intervention 2: Intervention group: Lidocaine 0.5%, 3 mg/kg (maximum 200 mg) for IVRA and 200 mcg TNG. Intervention 3:

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: indication of upper limb surgery ASA class I or II age 18 to 60

Exclusion criteria

Exclusion criteria: sickle cell anemia peripheral vascular disease such as Raynauds disease allergi to used drugs

Design outcomes

Primary

MeasureTime frame
The Visual Analogue Scale Scoring system (VAS). Timepoint: Every 15 minutes after the start of the block until one hour after entering recovery. Method of measurement: Visual Analogue Scale (VAS) (0 = no pain and 10 = worst pain imaginable).—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Mohammad Reza Safavi

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 3822 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026