The effect of Apotel and Ketorolac on pain after surgery

Preemptive comparative study of the effect of Apotel and intravenous Ketorolac on pain after laparoscopic cholecystectomy surgery under general anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101211005362N30

Enrollment

Registered

2022-04-26

Start date

2022-03-19

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after laparoscopic cholecystectomy.

Interventions

Intervention 1: Intervention group: Patients receive 30mg of intravenous Ketorolac in 50cc normal saline before surgical incision. Intervention 2: Intervention group: Patients receive 2gr of Apotel in

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patients aged 18-65 years for laparoscopic cholecystectomy under general anesthesia with ASA class 1 and 2

Exclusion criteria

Exclusion criteria: addiction underlying disease drug allergy

Design outcomes

Primary

Measure	Time frame
VAS. Timepoint: Visual Analogue Scale is assessed at 1, 2, 3, 4, 8, 12, and 24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Reza Safavi Homami

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 1668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026