Comparison between Rosemary gargle versus Lidocaine gargle on sore throat and voice violence after endotracheal intubation under general anesthesia in candidates patients for surgeries

A Comparative study of the preoperative effects of Rosemary gargle versus Lidocaine gargle on sore throat and voice violence after endotracheal intubation under general anesthesia in candidates patients for surgeries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101211005362N29

Enrollment

Registered

2022-02-26

Start date

2022-02-20

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Sore throat. Condition 2: Hoarseness. Pain in throat Voice and resonance disorders

Interventions

Intervention 1: Intervention group: In group1 we will give gargle of 30 drops of Rosemary solution 5% (Aboureihan company) which will be diluted with 30 drops of distilled water 2-3 minutes before gen

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patient for surgery ASA 1,2 Age between 18 to 65 years old Informed consent of patient

Exclusion criteria

Exclusion criteria: ?IV or Opioid drugs addicts Previous Allergy to drugs (Rosemary,Lidocaine) Patients with Heart,Renal pr Hepatic failure Hard Intubation (Grade 4 or upper) Malformation of airway tract

Design outcomes

Primary

Measure	Time frame
Intensity of sore throat based on VAS scale. Timepoint: Every 15 minutes at recovery, every 2 hours in first 6 hour and then at 12 and 24 hours after operation. Method of measurement: Visual Analogue Scale.;Intensity of voice violence. Timepoint: Every 15 minutes at recovery, every 2 hours in first 6 hour and then at 12 and 24 hours after operation. Method of measurement: Grade, Roughness, Breathiness, Asthenia, Strain Scale (voice disorder assessment).	—

Measure

Time frame

Intensity of sore throat based on VAS scale. Timepoint: Every 15 minutes at recovery, every 2 hours in first 6 hour and then at 12 and 24 hours after operation. Method of measurement: Visual Analogue Scale.;Intensity of voice violence. Timepoint: Every 15 minutes at recovery, every 2 hours in first 6 hour and then at 12 and 24 hours after operation. Method of measurement: Grade, Roughness, Breathiness, Asthenia, Strain Scale (voice disorder assessment).

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Secondary

Measure	Time frame
Average satisfaction level of patients. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.;Average of first time liquids regime toleration. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.;Average of first time solids regime toleration. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.	—

Measure

Time frame

Average satisfaction level of patients. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.;Average of first time liquids regime toleration. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.;Average of first time solids regime toleration. Timepoint: First 48 hours after operation. Method of measurement: Hours count that will be measured by researcher.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammadreza Safavi Homami

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir009836683221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026