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Comparison of the effect of lidocaine, ketamine and Altadine on sore throat

Comparative study of lidocaine gargle, ketamine gargle, single dose of Altadine tablets and control group on sore throat in patients under general anesthesia after endotracheal intubation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101211005362N28
Enrollment
300
Registered
2022-02-13
Start date
2022-01-16
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Postoperative sore Throat( POST ). Condition 2: Postextubation cough. Pain in throat Cough

Interventions

Intervention 1: Intervention group: in the first intervention group ,for gargling lidocain ,1 mg per kg in 30cc of distilled water is given to the patient to gargle once. Intervention 2: Intervention

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Hospitalized patients 18 to 60 years Candidate for surgery under 1 hour Candidate for intubation in the supine position

Exclusion criteria

Exclusion criteria: Use of anti-inflammatory drugs for two weeks before surgery History of upper airway infection and sore throat Prolonged operation more than an hour The patient is psychopathic Diabetic patients Drug allergy Difficult Intubation

Design outcomes

Primary

MeasureTime frame
Severity of sore throat based on visual analogue scale system. Timepoint: measurement of sore throat at the begining of the study and 2, 6 and 24 hours after taking the drug. Method of measurement: questionnaire visual analogue scale.

Secondary

MeasureTime frame
Itchy throat. Timepoint: existence of itchy throat at the begining of the study and 2, 6 and 24 hours after taking the drug. Method of measurement: question from patient.;Cough. Timepoint: existence of cough at the begining of the study and 2, 6 and 24 hours after taking the drug. Method of measurement: question from patient.

Countries

Iceland

Contacts

Public ContactMohammadreza Safavi

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 1273 2659

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026