Effect of local Hydrocortisone on pain and nausea and vomiting after surgery

Comparative study of the effect of local infiltration of two doses of Hydrocortisone on pain and nausea and vomiting after laparoscopic cholecystectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101211005362N26

Enrollment

105

Registered

2021-07-07

Start date

2021-04-21

Completion date

Unknown

Last updated

2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Post operative pain. Condition 2: Post operative nausea and vomiting. Other acute post procedural pain Vomiting following gastrointestinal surgery

Interventions

Intervention 1: Intervention group 1: consists of 35 people receiving 100 mg of hydrocortisone who receive the drug once and as a preemptive by local infiltration at the site of laparoscopic cholecyst

Eligibility

Sex/Gender

All

Age

20 Years to 85 Years

Inclusion criteria

Inclusion criteria: Age group 85-20 years Case of laparoscopic cholecystectomy due to chronic cholecystitis ASA physical status one and two

Exclusion criteria

Exclusion criteria: Patients with allergies to local anesthetics and drugs, morbid obesity, advanced respiratory diseases, kidney, blood, liver, cardiovascular Chronic drug use, beta or alcohol adrenergic receptor antagonists, and drug addicts pregnant women Mental retardation

Design outcomes

Primary

Measure	Time frame
Pain Visual Analogue Scale score. Timepoint: In recovery every 15 minutes and up to 24 hours after surgery every 6 hours. Method of measurement: Visual Analogue Scale score.	—

Secondary

Measure	Time frame
Post operative nausea and vomiting Visual Analogue Scale score. Timepoint: In recovery every 15 minutes and up to 24 hours after surgery every 6 hours. Method of measurement: Visual Analogue Scale score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammadreza Safavi

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 3620 1992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026