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effect of remifentanil in general anesthesia

Specify the effect of intranasal and intravenous remifentanil on hemodynamic changes after induction and tracheal intubation and comparing with control group

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101211005362N24
Enrollment
180
Registered
2020-06-06
Start date
2018-03-21
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes after induction of anesthesia.

Interventions

Intervention 1: Intervention group: The first intervention group consisted of 60 recipients receiving 0.5 micrograms intravenous remifentanyl. Intervention 2: Intervention group: The second group inc

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patient with ASA1.2 Patient between 18 to 65 years old Patients who need General anesthesia and larengoscopy and tracheal intubation

Exclusion criteria

Exclusion criteria: Patients under 18 or older than 65 years old Addicted patients Patients who have allergy to the drug noticed in this study Patient with ASA3.4

Design outcomes

Primary

MeasureTime frame
Mean systolic and diastolic blood pressure and mean arterial blood pressure. Timepoint: Basic time (just before the intervention) 1-3 minutes after anesthesia just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy. Method of measurement: Non-invasive manometer.;Heart rate. Timepoint: At baseline (before the intervention) 1 to 3 minutes after anesthesia just before laryngoscopy and at 1-3-5-10 minutes after laryngoscopy. Method of measurement: electro cardiogaraph.;Average of satisfaction score. Timepoint: after surgery. Method of measurement: Visual Analogue Scale.;Average of O2 saturation. Timepoint: Basic time (before the intervention) 1 to 3 minutes after anesthesia just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy. Method of measurement: pulse oxymeter.;Capnography. Timepoint: Basic time (before the intervention) 1 to 3 minutes after anesthesia just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy. Method of measurement: capnograph.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Safavi

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 1273 2659

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026