oral celecoxib on shivering during and after orthopedic lower extremity surgery

A Comparison of the preventive effect of 100 mg and 200 mg oral celecoxib on shivering during and after orthopedic lower extremity surgery under the spinal anesthesia in patients and the control group

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101211005362N23

Enrollment

105

Registered

2020-03-25

Start date

2016-05-21

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Hypothermia following anesthesia

Interventions

Intervention 1: First intervention group: received Celecoxib 100mg three hours before operation. Intervention 2: Second intervention group: received Celecoxib 200mg three hours before operation. Inter

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: the patients with American Society of Anesthesiologists (ASA) 1 age between 18 and 65

Exclusion criteria

Exclusion criteria: History of hypertension Sever cardiovascular disease Allergy to Coxib drugs Psychological disorder based on history Temperature less than 36 or more than 38 Celsius degree Usage of alcohol and opioids Usage of vasodilators Allergy to Aspirin

Design outcomes

Primary

Measure	Time frame
Incidence and severity of shivering based on Tsai and Cha scale. Timepoint: every 15 minutes. Method of measurement: objective.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohamadreza Safavi

Esfahan University of Medical Sciences

safavi@med.mui.ac.ir+98 31 3620 1992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026