Comparison of the effect of Persica mouthwash and normal saline in reducing ventilator-induced respiratory infection

Comparison of the effect of Persica mouthwash and normal saline on the reduction of ventilator-induced respiratory infections in hospitalized children

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101207005335N2

Enrollment

Registered

2022-01-22

Start date

2019-04-21

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduce ventilator infection. ????????? ????? ????? ? ????????

Interventions

Intervention 1: Intervention group: Patients who were placed under a ventilator after admission to the ICU and Persica mouthwash was used for mouthwash for 5 days. Persica mouthwash with the scientifi

Eligibility

Sex/Gender

All

Age

1 Months to 14 Years

Inclusion criteria

Inclusion criteria: The patient’s age should be between1 month and 14 years old The patient had to be admitted to the intensive care unit in Less than 12 hours He/she had not been hospitalized in any other wards before being admitted to the ICU. He/she did not take antibiotics before admission, had no history of allergies to plant compounds, had no chronic disease and immune system disorder, as well as any specific damage caused by endotracheal intubation or airway. He/she had no specific lesion in or around the mouth.

Exclusion criteria

Exclusion criteria: Causes any specific damage by endotracheal intubation or airway or any other physical factor The patient's legal guardian is unwilling to enter the study.

Design outcomes

Primary

Measure	Time frame
Body temperature. Timepoint: Done in 5 days. Four times a day every 6 hours,. Method of measurement: Mercury Therommeter.;White blood cell count. Timepoint: It was performed four times a day every 6 hours for 5 days. Method of measurement: Based on the patient's blood test result (CBC).;Blood oxygenation. Timepoint: It was performed four times a day every 6 hours for 5 days. Method of measurement: Based on the blood pulse oximetry shown by the monitoring device.;Chest radiography. Timepoint: Before the intervention and after the intervention. Method of measurement: Chest radiography.;Culturing tracheal secretions and scoring them in the Clinical benchmark of Lung infection (cpis). Timepoint: Before the intervention and after the intervention. Method of measurement: Clinical Pulmonary Infection Score.	—

Measure

Time frame

Body temperature. Timepoint: Done in 5 days. Four times a day every 6 hours,. Method of measurement: Mercury Therommeter.;White blood cell count. Timepoint: It was performed four times a day every 6 hours for 5 days. Method of measurement: Based on the patient's blood test result (CBC).;Blood oxygenation. Timepoint: It was performed four times a day every 6 hours for 5 days. Method of measurement: Based on the blood pulse oximetry shown by the monitoring device.;Chest radiography. Timepoint: Before the intervention and after the intervention. Method of measurement: Chest radiography.;Culturing tracheal secretions and scoring them in the Clinical benchmark of Lung infection (cpis). Timepoint: Before the intervention and after the intervention. Method of measurement: Clinical Pulmonary Infection Score.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Adib

Tehran University of Medical Sciences

Zahraadib@yahoo.com+98 34 3223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026