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The role of H.Pylori in persistent idiopathic chronic urticaria and responses to treatment

Treatment effectiveness of H.Pylori in persistent idiopathic chronic urticaria and responses to treatment in pediatrics

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201012065330N1
Enrollment
120
Registered
2011-04-07
Start date
2010-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chronic urticaria. Condition 2: Helicobacter pylori. Condition 3: Gastritis. Utricaria Other specified bacterial agents as the cause of diseases classified to other chapters Gastritis and duodenitis

Interventions

Intervention 1: Triple therapy consisting of amoxicillin (50 mg.kg a day), metronidazol (30 mg .kg a day) and omeprazole (1mg.kg a day) was administered to H.pylori-positive patients at the time of d
Treatment - Drugs
Triple therapy consisting of amoxicillin (50 mg.kg a day), metronidazol (30 mg .kg a day) and omeprazole (1mg.kg a day) was administered to H.pylori-positive patients at the time of diagnosis for 2 w
Uninfected patients (UBT negative)were used as a control group. clinical features of urticaria symptoms were evaluated the same of H. pylori infection positive groups.

Sponsors

Vice chancellor for research, Tabriz University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 20 Years

Inclusion criteria

Inclusion criteria: All patients (4-20 years old) affected by idiopathic chronic urticaria were included. The following patients were excluded: 1) those with other current or recent serious diseases. 2 ) those had received H.Pylori treatment. 3)those who had received antibiotics or bismuth treatment in the two months before enrollment or K1 ,H1-ATPase inhibitors two weeks before enrollment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Idiopathic chronic urticaria. Timepoint: 2 m. Method of measurement: Each variable was graded from 0 (absent) to 3 (severe) . A patient self-evaluation of each symptom was also recorded, by rating the severity of wheals, erythema, and daily and nocturnal pruritus on a 4-point scale: 0 (absent) , 1 (mild), 2 (moderate), 3 (seve re).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohamad Somi

liver and gastrointestinal research center, Tabriz university of medical sciences

liver_gastrology@yahoo.com+98 41 1336 7473

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026