Cervical ripening and induction of labor.
Conditions
Interventions
Intervention 1: vaginal administration oral tablet isosorbite mononitrate 20 mg, two tablets per 12 hours before start of induction of labor with oxytocin in interventional group. Intervention 2: In p
Treatment - Drugs
Placebo
vaginal administration oral tablet isosorbite mononitrate 20 mg, two tablets per 12 hours before start of induction of labor with oxytocin in interventional group
In plasebo group: to give plasebo tablet made of caco3, Odisel, Mg estearate 1% that will be made by Ahvaz Faculty of pharmacy, 24 hours before start of induction of labor with oxytocin
Sponsors
Research Deputy, Ahvaz Jondishapur university of medical science
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 18-35, nullipara, Bishop sore equal or low of 5, To have Reliable LMP or sonography in first trimester, To have BMI 19.6-26 in first trimester, Cephalic presentation, Fetal Weigth=2500-4000, single fetus, To have NST and biophysical profil in last 48 hours, Gestational age: 40-42 w Exclusion criteria: Congenital abnormalitywith sono in the second trimester, preclampsia, Headache, post C/S, Active genital herpes, Addict to alcohol, polyhydroamnios, placenta previa or doubt to placenta abruption, previous breath or heard disease, to have any conterindication for induction of labor, BPs<90
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cervical ripening. Timepoint: 24 hours. Method of measurement: measurement of cervix bishop score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamideh Yazdizadeh
Ahvaz Jondishapur university of medical science - Faculty of nursing and midwifery
Outcome results
None listed