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Comparative study of tranexamic acid

Comparative study of tranexamic acid on the prevention and decrease of Postpartum Hemorrhage in high-risk women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101130005280N44
Enrollment
214
Registered
2021-12-14
Start date
2021-11-21
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occurrence of postpartum hemorrhage.

Interventions

Intervention 1: Intervention group: In the intervention group, one gram of tranexamic acid will be injected immediately after delivery.Bleeding rate in the first 2 hours, 12 and 24 hours after deliver

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: For pregnant mothers between 37-40 weeks, age between 20 to 40 years Satisfaction to participate in the study History of postpartum hemorrhage in previous pregnancy Macrosomic more than 4 kg Polyhydramnios History of thromboembolic events Lower limb varicose veins aggregate more than 24 hours Very fast labor and high parity Chorioamnionitis and placental abruption

Exclusion criteria

Exclusion criteria: Multiple pregnancies Placental abnormalities Preeclampsia Liver disorders Kidney, brain and ...

Design outcomes

Primary

MeasureTime frame
The amount of bleeding. Timepoint: In the first 2 hours (each quarter) and 12 and 24 hours after delivery. Method of measurement: Measure the amount of blood lost.;The amount of hemoglobin drop in both groups. Timepoint: In the first 2 hours (each quarter) and 12 and 24 hours after delivery. Method of measurement: The amount of hemoglobin is checked before and after delivery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoda Hosseini

Mashhad University of Medical Sciences

Hoseinih961@mums.ac.ir+98 51 3841 3492

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026