The effect of transcranial direct current stimulation on cognitive functions in patients with bipolar disorder

Investigation of the effect of transcranial direct current stimulation on cognitive functions in patients with bipolar disorder

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101130005280N34

Enrollment

Registered

2020-09-20

Start date

2020-07-05

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder. Bipolar disorder

Interventions

Intervention 1: Intervention group: In this group, the anode is placed in the left prefrontal cortex and the cathode in the right cerebellar region (based on the 10/20 system) at 2 mA for 20 minutes f

Eligibility

Sex/Gender

All

Age

18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Patients with bipolar disorder in the euthymic phase between 18 to 42 years old No being in the manic and depression phase through analyzing the HDRS and YMRS questionnaires Patients must have disorders in several cognitive domains. The patient has no other psychiatric disorder or problem. The patient has not received shock therapy during the past year.

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Cognitive functions. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Stroop test.;Attention. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Digit span test.;Memory. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Rey auditory verbal Learning test and Rey–Osterrieth complex figure.	—

Measure

Time frame

Cognitive functions. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Stroop test.;Attention. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Digit span test.;Memory. Timepoint: At the beginning of the intervention, first, second, third and seventh week. Method of measurement: Rey auditory verbal Learning test and Rey–Osterrieth complex figure.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Talaei

Mashhad University of Medical Sciences

talaeia@mums.ac.i+98 51 3711 2709

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026