Efficacy of five-finger combine extract and Hazel Extract in the treatment of female sexual dysfunction

Study of the efficacy of five-finger combine extract (Vitex Agnus Castus) and Hazel (Lupulus Humulus) Extract compared with Bupropion in the treatment of female sexual dysfunction due to serotonin reuptake inhibitors

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101130005280N29

Enrollment

Registered

2019-09-21

Start date

2019-06-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sexual function. Sexual dysfunction not due to a substance or known physiological condition

Interventions

Intervention 1: Intervention group: Intervention in group 1 contains Taking one halves of the extract of Vitex Agnus Castus and Lupulus Humulus every 12 hours one an hour after meals for a period of f

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: patients aged 18-60 years old All women treated with SSRI who developed or exacerbated the symptoms of sexual dysfunction after taking the drug Completion of informed consent form Lack of medical illness (neurology and ...) Lack of bipolar history, psychosis and ... No narcotics use No other interfering drugs use

Exclusion criteria

Exclusion criteria: A hypersensitivity reaction or any intolerable side effects caused by the drug Unwillingness to continue the study and taking medication

Design outcomes

Primary

Measure	Time frame
Sexual function. Timepoint: Before starting treatment at the beginning of the second week and at the end of the course, the women's sexual function will be evaluated by a questionnaire in both groups. Method of measurement: women's sexual function questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Gilan

Mashhad University of Medical Sciences

GilanA951@mums.ac.ir+98 51 3711 2701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026