Effect of Adding Sina Curcumin to Sertraline in Treatment of Depression

Assessment of the Effect of Adding Sina Curcumin to Sertraline in Treatment of Major Depressive Disorder

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101130005280N26

Enrollment

Registered

2018-03-19

Start date

2017-01-29

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder. Major depressive disorder, single episode, severe without psychotic features

Interventions

Intervention 1: Control group: placebo, once per day, 8 weeks. Intervention 2: Intervention group: Sina Curcumin, 80 milligrams, once per day, 8 weeks.

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Having diagnostic criteria for Major Depressive Disorder Aged between 18-50 years Written consent form

Exclusion criteria

Exclusion criteria: History of suicide or having suicidal thoughts Psychosis Substance abuse Taking other drugs Neurological diseases History of head trauma Creating side effects

Design outcomes

Primary

Measure	Time frame
Depression. Timepoint: Baseline, 4th WEEK, 8th week. Method of measurement: Beck Depression Inventory.;Anxiety. Timepoint: Baseline, 4th WEEK, 8th week. Method of measurement: Beck Anxiety Inventory.	—

Secondary

Measure	Time frame
Side effects. Timepoint: 4th week, 8th week. Method of measurement: Side Effects Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Noori

Mashhad University of Medical Sciences

pbsrc@mums.ac.ir+98 51 3711 2540

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026