chronic anal fissure. chronic anal fissure
Conditions
Interventions
Intervention 1: Intervention group: the patients set in knee chest position and single dose of botax, under local anesthesia is injected (25units) in internal sphincter in sitution of 3 and 9 o'clock.
Treatment - Drugs
Treatment - Surgery
Intervention group: the patients set in knee chest position and single dose of botax, under local anesthesia is injected (25units) in internal sphincter in sitution of 3 and 9 o'clock.
Control group: the patients set in trendelenberg position and under general anesthesia about 30 percent of internal muscle sphincter (in 3 oclock sitution) was ligated with knife (number 15)
Sponsors
Vice- chancellor for Reasearch of Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: diagnosis of chronic anal fissure (presented greater than 6 weeks), presence of triad of (sentinel pile, hypertrophy of papi and fibrosis of bed wound), age between18 and 100 years old Exclusion criteria: combination with other anal diseases such as: hemorrhoid, anal fistula, rectal prolapse and positive history of anorectal surgery, positive history of neuromuscular diseases (myesthenia gravis, multiple sclerosis, amiotrophic lateral sclerosis), breast feeding, pregnancy, positive history of drug consumption consist of aspirin, warfarin, aminoglycosides, chloroquine, aminoglycosides, chloroquine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing. Timepoint: one week and two months after discharge. Method of measurement: Complete Wound Healing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications. Timepoint: One week and two month after discharge. Method of measurement: Standard form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hamid Reza Fereidoonin
Hamedan University of Medical Sciences
Outcome results
None listed