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Prevention of infection after cesarean

Comparison of single dose versus three doses antibiotic prophylaxis regimen for cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011275259N1
Enrollment
146
Registered
2011-01-04
Start date
1996-10-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection following cesarean section. Infection following a procedure

Interventions

Intervention 1: Cefazolin 2 g/IV single-dose, in the operating room after clamping the umbilical cord. Intervention 2: Cefazolin 2 g/IV, three doses, after clamping the cord, 6 hours and 48 hours afte
Prevention
Cefazolin 2 g/IV single-dose, in the operating room after clamping the umbilical cord
Cefazolin 2 g/IV, three doses, after clamping the cord, 6 hours and 48 hours after cesarean section

Sponsors

Deputy research of Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
14 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: the number of vaginal examination of hospital stay less than or equal to four times, rupture of membranes for six hours or less, duration of hospitalization less than 24 hours, duration of surgery less than 60 minutes, gestational age more than 36 weeks, body mass index of less than 30. Exclusion criteria: Fever prior to cesarean section, urinary symptoms, no possibility to follow-up for 10 days after the operation, presence of underlying diseases such as diabetes and hypertension, receiving oral or intravenous antibiotics before surgery due to other causes, cesarean due to lack of progress in the second stage of labor, history of corticosteroid use

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Symptoms of infection. Timepoint: During the hospital stay after a cesarean every six hours and then discharged on day 10. Method of measurement: check of Of fever, chills, cellulitis incision, discharge and tenderness of uterine incision.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmadreza Mobaien

Zanjan University of Medical Sciences

amobaien@yahoo.com+98 912 619 1730

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026