Recurrent aphthous stomatitis. recurrent aphthous stomatitis
Conditions
Interventions
Intervention 1: Intervention group: Bioadhesive paste Containing Licorice 5% 4 times per days 1h before meal and 20 minutes before sleep. Intervention 2: Control group: diphen hydramin elixir, 5 cc, 4
Treatment - Drugs
Intervention group: Bioadhesive paste Containing Licorice 5% 4 times per days 1h before meal and 20 minutes before sleep
Control group: diphen hydramin elixir, 5 cc, 4 times per days 1h before meal and 20 minute before sleep
Control group: Bioadhesive paste without Licorice 5%, 4 times per days 1h before meal and 20 minute before sleep
Sponsors
Zahedan University of Medical Siences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: history of recurrent aphthous stomatitis, Current suffering from ulceration in 1 day, signed a well-explained written informed consent form Exclusion criteria: Pregnancy, lactation (Urine hCG-positive), Ulcers as a manifestation of a systemic disease process such as ulcerative colitis, Crohn's disease, Behcet's syndrome, serious anemia, treatment with systemic steroid or other immunomodulatory agents within 1 month before the study entry, ulcer in tongue, major RAS, presenting with more 1 aphthous ulcers, after 24 hours' duration of ulcer
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diameter of the lesion with erythematois rim. Timepoint: 48 hours. Method of measurement: periodental prob.;Diameter of necrotic zone. Timepoint: 48 hours. Method of measurement: periodental prob.;Pain level. Timepoint: 48 hours. Method of measurement: visual analoge scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarjes Akbare
Zahedan University of Medical Sciences,
Outcome results
None listed