Alendronate effects in patients with lumbar spine fracture

Results of alendronate administration in patients with lumbar spine fracture without surgical indication

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101122005230N3

Enrollment

Registered

2019-07-28

Start date

2019-06-26

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after surgery. Low back pain

Interventions

Intervention 1: Intervention group: After discharge, patients will receive weekly 35 mg of alendronate at a dose of 70 mg per week. Intervention 2: Control group: Patients will receive analgesics.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Lack of Indication for Surgery based on Thoracolumbar injury classification severity score Spinal cord fracture according to Denis model in CT Scan Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Pathological fractures Fractures in several vertebrae Simultaneous head trauma and neurological status of the patient in such a way that it is not possible to have a neurological examination at the time of admission Neural failure before spinal trauma Fracture-type fracture-dislocation Disturbed results of calcium and serum vitamin D tests (osteoporosis)

Design outcomes

Primary

Measure	Time frame
Pain after surgery. Timepoint: 6 months after surgery. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Moslem Shakery

Tabriz University of Medical Sciences

shakerym@tbzmed.ac.ir+98 41 1333 7927

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026