The effect of naloxone on hemodynamic factors and bleeding rate in patients under general anesthesia.

Comparison of the effect of low-dose naloxone infusion on hemodynamic factors and surgical field bleeding in patients under general anesthesia with remifentanil and propofol infusion.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101122005225N10

Enrollment

114

Registered

2022-05-09

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck surgery. Diffuse follicle center lymphoma, lymph nodes of head, face, and neck

Interventions

Intervention 1: Intervention group: This study is a randomized clinical trial and will be performed after the approval of the ethics committee of Tehran University of Medical Sciences. After prescribi

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing head and neck surgery

Exclusion criteria

Exclusion criteria: Patients addicted to Narcotics Patients with heart failure or advanced heart disease Patients with asthma

Design outcomes

Primary

Measure	Time frame
Dose of narcotics. Timepoint: During the operation. Method of measurement: View and record.	—

Secondary

Measure	Time frame
Surgeon satisfaction with bleeding during surgery. Timepoint: During the operation. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Mireskandari

Tehran University of Medical Sciences

mireskandari@sina.tums.ac.ir+98 21 2261 8931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026